PCB Technical - What is the long-term relationship between line spacing and PCB:

What is the long-term relationship between line spacing and PCB:
The miniaturization of increasingly important electronic circuits is pushing PCB makers to reduce size and increase the density of components on their boards.This helps to make things smaller and limits manufacturing costs.This way of thinking is not limited to handheld devices, but to the entire consumer electronics industry around the world.However, the miniaturization of electronic circuits may present several challenges for PCB manufacturers.
Minimum distance to avoid flashover between electrical conductors or tracking faults.Electronic circuits that do not require shock protection can be printed with smaller spacing between tracks.The key factors to determine the spacing are the use of insulating materials and the use of double-sided assembly.
Several factors that affect creepage distance and clearance include: working voltage, pollution, insulation material, circuits.